Peripheral T-Cell Lymphoma
PTCL is classified as a subtype of non-Hodgkin's lymphoma (NHL). NHL affects two particular types of white blood cells: B-cells and T-cells. PTCL specifically affects T-cells, and results when T-cells develop and grow abnormally. It is PTCL's origin in the lymphatic system that gave it the name peripheral T-cell lymphoma.
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Peripheral T-Cell Lymphoma, not Otherwise Specified (PTCL …
PTCL-NOS is a diagnosis of exclusion, comprising several disease entities that differ in biology, clinical presentation, and outcome. The diagnosis of PTCL-NOS is made based on the presence of typical histopathological features of lymphoma, an aberrant T-cell immunophenotype, often with a loss of CD5 and CD7, and a clonal T-cell receptor (TCR ...